Prime^™ Astaxanthin Cardio Visual Vitality Formula uses AstaReal^® astaxanthin. With high quality and stability, AstaReal^® astaxanthin ranks among the purest and most powerful antioxidants available. AstaReal^® uses precision cultivation techniques in state-of the-art facilities, producing only 100 percent natural astaxanthin in a purified, sterile environment.*

Prime Astaxanthin Cardio & Visual Vitality Formula delivers a 6 mg serving of this high-grade astaxanthin in a single serving, providing the optimal amount in every pill. This makes Prime Astaxanthin a giant step forward in the longevity revolution through its unequaled ability to combat free radicals at the cellular level.*

The power of Prime Astaxanthin to fight free radicals is of critical importance, but it must also be delivered to the body in sufficient amounts to be truly effective. Typical astaxanthin formulations contain only 2-4 mg per serving — an amount which falls short in delivering all possible benefits for the heart, eyes, skin and muscles. Prime Astaxanthin Cardio & Visual Vitality Formula is made exclusively in a 6 mg serving, which is superior for promoting optimal cardiovascular function, supporting healthy vision and skin, blood flow and muscular endurance.* Together, the quantity and the quality delivered by Prime Astaxanthin yields anti-aging benefits second to none.

Daily exposure to free radicals — contained within the air we breathe and the food we eat — results in ongoing, long-term physical stress. The widespread oxidative stress they cause to all systems of the body is also believed to be a primary contributor to what we call the aging process. Prime Astaxanthin works against free radicals by providing powerful antioxidant defense to help protect the entire body on a cellular level.

*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.

^‡As AstaReal^®. AstaReal is a registered trademark of Fuji Chemical Industry Co., Ltd.

Astaxanthin (AstaReal^® P2 AF 2%)
Astaxanthin is a carotenoid that gives the reddish pigment to salmon, crab, krill and lobster. It is known for its powerful antioxidant effects and has been shown to be a superior free radical quencher when compared to other antioxidants like vitamin C, coenzyme Q10 and green tea. Astaxanthin’s unique structure includes long chains which allow it to cover the cell membrane and provide antioxidant protection in all layers, whereas other antioxidants are more limited. Japanese who are the uppermost consumers of food containing astaxanthin (AX) in the world and have the lowest incidences of heart diseases amongst developed countries. In addition, a growing body of scientific evidence points to a strong link between natural astaxanthin and cardiovascular health. There have been 30 cardiovascular-specific research publications, including 10 clinical studies, investigating possible benefits of astaxanthin on both blood lipid levels and blood vessels. These studies have shown that astaxanthin helps maintain normal levels of HDL and triglycerides when consumed orally. Three recent clinical studies support astaxanthin’s ability to help maintain healthy blood vessels. Other recent human studies indicate that astaxanthin supports cardiovascular health. A series of human studies suggest that astaxanthin helps maintain healthy blood pressure by promoting healthy blood flow and vascular tone. Astaxanthin supports cardiovascular health in several ways. In addition to its effects on cardiovascular health, astaxanthin promotes healthy visual accommodation and retinal capillary blood flow. The exact mechanism by which astaxanthin supports vision is unknown, though some believe that by promoting blood flow to the ciliary body, it provides nourishment for the ciliary muscles. Astaxanthin is also believed to work by promoting normal NF-kB activation by oxygen radicals, which may explain how it helps to alleviate occasional eye fatigue.

• Camera, E., et al. Astaxanthin, canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes. Exp Dermatol. 18(3):222-31, 2009.
• Choi et al. Effects of astaxanthin on oxidative stress in overweight and obese adults. Phytother Research (in-press), 2011.
• Ikeuchi, M., et al. Effects of astaxanthin supplementation on exercise-induced fatigue in mice. Bio. Pharm. Bull. 29(10):2106-2110, 2006.
• Karppi, et al . Effects of astaxanthin supplementation on lipid peroxidation. Int J Vitam Nutr. Jan; 77 (1): 3-11, 2007.
• Malmsten, C. and Lignell, A. Dietary supplementation with astaxanthin rich algal meal improves muscle endurance – a double blind study on male students. Carotenoid Science. 13:20-22, 2008.
• Matsuyama, et al . A safety study on the long-term consumption of astaxanthin in healthy human volunteer. Japanese Journal of Complementary and Alternative Medicine. (7):43-50, 2010.
• Miyawaki, et al . Effects of astaxanthin on human blood rheology. Journal of Clinical Therapeutics and Medicines. 21(4):421-429, 2005.
• Nagaki, Y., et al. Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers. Journal of Traditional Medicines. 19: 170-173, 2002.
• Nagaki, Y., et al. Effects of astaxanthin on retinal capillary blood flow in normal volunteers. Journal of Clinical Therapeutics and Medicines. 21(5): 537-542, 2005.
• Naguib, Y. The antioxidant activities of astaxanthin and related carotenoids. Journal of Agricultural and Food Chemistry. 48(4): 1150-1154, 2000.
• Nakagawa, et al . Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes. British Journal of Nutrition. (31):1-9, 2011.
• Nakamura, A., et al. Changes in visual function following peroral astaxanthin. Japanese Journal of Clinical Ophthalmology. 58(6): 1051-1054, 2004.
• Satoh, et al. Preliminary clinical evaluation of toxicity and efficacy of a new astaxanthin-rich Hameotoccus pluvialis . J. Clin. Biochem. Nutr. 44: 280–284, 2009.
• Sawaki, K., et al. Sports performance benefits from taking natural astaxanthin characterized by visual activity and muscle fatigue improvements in humans. J. Clin. Ther. Med. 18(9):73-88, 2002.
• Yamashita, et al. Cosmetic benefit of the supplement health food combined astaxanthin and tocotrienol on human skin. Food Style. 21. 6(6):112-117, 2002.
• Yamashita, et al. The Effects of a Dietary Supplement Containing Astaxanthin on Skin Condition. Carotenoid Science. 10:91-95, 2006.